The ATO cell culture system mimics the function of the human thymus to allow differentiation of fully functioning T cells from hematopoietic stem cells. Importantly, the ATO cell culture system allows engineering of the T-cell receptor during T-cell differentiation, making the system potentially suitable for the generation of off-the-shelf engineered T cells from renewable cell source.
The publication, "Generation of mature T cells from human hematopoietic
stem and progenitor cells in artificial thymic organoids", was published
online in Nature Methods on
Kite is a biopharmaceutical company engaged in the development of innovative cancer immunotherapies with a goal of providing rapid, long-term durable response and eliminating the burden of chronic care. The company is focused on chimeric antigen receptor (CAR) and T cell receptor (TCR) engineered cell therapies designed to empower the immune system's ability to recognize and kill tumors. Kite is based in Santa Monica, CA. For more information on Kite, please visit www.kitepharma.com. Sign up to follow @KitePharma on Twitter at www.twitter.com/kitepharma.
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statements regarding intentions, beliefs, projections, outlook, analyses
or current expectations concerning, among other things: the potential of
the artificial thymic organoid cell culture system to generate
off-the-shelf engineered T cells to treat cancer and other diseases.
Various factors may cause differences between Kite's expectations and
actual results as discussed in greater detail in Kite's filings with the
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